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Anna received her B.S. (1989) and PhD (1993) from the Biophysics Department of Moscow State University in Russia, where she studied protein dynamics by Mossbauer spectroscopy. She came to the USA as an NSF visiting fellow and subsequently worked as a post-doctoral fellow in the School of Chemical Science of the University of Illinois at Urbana- Champaign. While at UIUC, she studied the kinetics of ligand binding to myoglobin and protein folding.

In September 1997 Anna joined NCBI of the National Institutes of Health, USA, as an IRTA Research Fellow, later as a Staff Scientist and then as a Lead Scientist. Her team worked on the development of computational algorithms for the analysis of protein sequence and structure, protein-protein interactions, identifying cancer driver events and nucleosome dynamics. In July 2019 she was recruited to the Queen's University School of Medicine where currently she leads her team through uncharted waters in computational biology and biophysics.

Yunhui Peng, Postdoctoral Fellow, NCBI, NIH (co-supervised with Dr David Landsman)

March 2019 -

Yunhui Peng received B.S. from Xi'an Jiaotong University in China and PhD in Computational Biophysics from Clemson University, USA. During his graduate work he applied computational approaches to investigate the effects of disease-associated missense mutations and further rescue the effects by small molecule binding. Currently he is working on combining computational molecular modeling and experimental data to investigate the nucleosome dynamics and its relation to DNA damage and repair.

Shuxiang Li, Postdoctoral Fellow

October 2019 -

Shuxiang Li received his B.S. from the Central China Normal University with majors in Chemistry and Biology and his Ph.D. in Biochemistry from the University of Iowa, USA. Later, he worked for two years as a postdoctoral fellow at Rutgers University, USA, where he developed computational methods for the analysis and modeling of nucleic acids and their interactions with proteins. Currently he is using high performance computing to develop approaches for studying the effects of epigenetic modifications on the structure, stability and dynamics of nucleosomes.

Daniel Espiritu, PhD student in Biomedical Informatics

Daniel received his B.S. from Queen’s University, with a major in life sciences and a specialization in drug development & human toxicology. During his undergraduate degree, Daniel investigated the effects of smoking on DNA methylation in chronic obstructive pulmonary disease patients. He is currently working on identifying driver statuses of cancer mutations in histones.

Daria Ostroverkhova, PhD student (co-supervised with Prof Konstantin Shaitan, Lomonosov Moscow State University)

Daria received her B.S. from the First Moscow Medical University, with a major in pharmaceutical sciences. During her undergraduate degree, Daria investigated a tumor-associated protein and mechanisms underlying interactions of the protein in complexes with estrogens and antiestrogens. Later, she worked for one year at Sechenov University, Russia, where she applied a molecular modeling approach for studying the regulation of calcium-sensing receptor, WNK kinases, and Na/K-ATPase. Currently, she is working on identifying driver epigenetic processes in human cancers.

Maria Korovina, Undergraduate student in Life Sciences

Maria is a 4th year student at Queen’s University studying Life Sciences with a specialization in biomedical discovery. She’s currently working on her 499 thesis project.